Nitric oxide, oxidative stress, and apoptosis
نویسندگان
چکیده
منابع مشابه
Depletion of nitric oxide causes cell cycle alterations, apoptosis, and oxidative stress in pulmonary cells.
Nitric oxide (NO ⋅) is important in the regulation of mitochondrial function, cell signaling, and gene expression. To elucidate how endogenous NO ⋅ regulates the function of airway epithelial cells, we used carboxy-PTIO, a hydrophilic, negatively charged NO ⋅ trap, to scavenge NO ⋅ from rat lung epithelial (RLE) and rat pleural mesothelial (RPM) cells and to determine the elicitation of cell cy...
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Tamoxifen is an anticancer drug that induces oxidative stress and apoptosis via mitochondria-dependent and nitric oxide (NO)–dependent pathways. The present report shows that tamoxifen increases intramitochondrial ionized Ca concentration and stimulates mitochondrial NO synthase (mtNOS) activity in the mitochondria from rat liver and human breast cancer MCF-7 cells. By stimulating mtNOS, tamoxi...
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Abstract Background and Objective: Recently, diabetes mellitus has been known as one of the main cause of upper gastrointestinal symptoms. Since a high prevalence of H. Pylori in diabetic patients has been reported, we aimed to evaluate the level of gastric juice Nitric Oxide (NO°), Oxidative Stress and Glycated Hemoglobin. Material and Methods: In case group, the participants were 60 diabe...
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Nitric oxide has been found to play an important role as a signal molecule in many parts of the organism as well as a cytotocic effector molecule of nonspecific immune response. Nitric oxide is very important functions both in helminthes and mammalian hosts. Nitric oxide may react with proteins and nucleic acids. In addition to binding to heme groups, e.g. of guanylate cyclase, hemoglobin, and ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2003
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.63.s84.6.x